Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ NMD Inhibitor
A cell-permeable inhibitor of nonsense-mediated mRNA decay (NMD) that enhances the stability of premature termination codon mutated p53 mRNA in N417 and HDQP-1 cells.
MilliporeSigma™ Calbiochem™ AhR Antagonist II, SR1
The AhR Antagonist II, SR1 controls the biological activity of AhR. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Ghrelin Receptor Antagonist, JMV 2959
A 1, 2, 4-triazole derived compound that acts as a potent ghrelin receptor (GHS-R1a) antagonist (IC50 = 32nM in a binding assay, dissociation constant Kb =
MilliporeSigma™ Calbiochem™ TLR1/TLR2 Antagonist, CU-CPT22
A cell-permeable benzotropolone compound that competes against Pam3 CSK4
MilliporeSigma™ Calbiochem™ SBHA
A cell-permeable bishydroxamic acid histone deacetylase (HDAC) inhibitor with anti-tumor properties.
MilliporeSigma™ Calbiochem™ PDGFR Tyrosine Kinase Inhibitor II
The PDGFR Tyrosine Kinase Inhibitor II, also referenced under CAS 249762-74-1, controls the biological activity of PDGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ PPARβ/δ Antagonist, GSK3787
The PPARβ/δAntagonist II, PT-S58, also referenced under CAS 188591-46-0, controls the biological activity of PPARβ/δ. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ TCPOBOP
The most potent known member of the phenobarbital-like class of cytochrome P450 (CYP)-inducing agents.
MilliporeSigma™ Calbiochem™ Methysergide Maleate
An antagonist of the 5-HT2B (pki
MilliporeSigma™ Calbiochem™ TLR3/dsRNA Complex Inhibitor
The TLR3/dsRNA Complex Inhibitor blocks dsRNA binding to TLR3.
MilliporeSigma™ Calbiochem™ HIF Inhibitor V
A cell-permeable phenoxyacrylamido compound that inhibits hypoxia-induced cellular HIF-1α accumulation in a manner similar to LW6 (Cat
MilliporeSigma™ Calbiochem™ InSolution™ Bcl-2 Inhibitor VI, ABT-737
A 25 mM (5 mg/246 μL) solution of Bcl-2 Inhibitor VI, ABT-737 in DMSO.
MilliporeSigma™ Calbiochem™ ERO1 Inhibitor I, Erodoxin
The ERO1 Inhibitor I, Erodoxin controls the biological activity of ERO1.
MilliporeSigma™ Calbiochem™ Glycogen Phosphorylase Inhibitor II, KB228
A mixed type inhibitor of muscle glycogen phosphorylase (Ki = 930 nM).
MilliporeSigma™ Calbiochem™ USP1-UAF1 Inhibitor, ML323
A cell-permeable, selective, potent, and reversible inhibitor of USP1-UAF1 deubiquitinase (IC50 = 76 nM in Ub-Rhodamine based assays). Does not disrupt USP1-UAF1 association.